Freezing of Gait in Parkinsonism and its Potential Drug Treatment
Identifieur interne : 000351 ( Main/Exploration ); précédent : 000350; suivant : 000352Freezing of Gait in Parkinsonism and its Potential Drug Treatment
Auteurs : Li-Li Zhang ; S. Duff Canning [Canada] ; Xiao-Ping WangSource :
- Current Neuropharmacology [ 1570-159X ] ; 2016.
Abstract
Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.
Url:
DOI: 10.2174/1570159X14666151201190040
PubMed: 26635194
PubMed Central: 4876585
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Freezing of Gait in Parkinsonism and its Potential Drug Treatment</title><author><name sortKey="Zhang, Li Li" sort="Zhang, Li Li" uniqKey="Zhang L" first="Li-Li" last="Zhang">Li-Li Zhang</name><affiliation><nlm:aff id="aff1">Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao-Tong University, China. 200080</nlm:aff><wicri:noCountry code="subfield">China. 200080</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, China. 210029</nlm:aff><wicri:noCountry code="subfield">China. 210029</wicri:noCountry></affiliation></author><author><name sortKey="Canning, S Duff" sort="Canning, S Duff" uniqKey="Canning S" first="S. Duff" last="Canning">S. Duff Canning</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Psychology University of Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychology University of Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Xiao Ping" sort="Wang, Xiao Ping" uniqKey="Wang X" first="Xiao-Ping" last="Wang">Xiao-Ping Wang</name><affiliation><nlm:aff id="aff1">Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao-Tong University, China. 200080</nlm:aff><wicri:noCountry code="subfield">China. 200080</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26635194</idno><idno type="pmc">4876585</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876585</idno><idno type="RBID">PMC:4876585</idno><idno type="doi">10.2174/1570159X14666151201190040</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000133</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000133</idno><idno type="wicri:Area/Pmc/Curation">000133</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000133</idno><idno type="wicri:Area/Pmc/Checkpoint">000125</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000125</idno><idno type="wicri:Area/Ncbi/Merge">001D94</idno><idno type="wicri:Area/Ncbi/Curation">001D94</idno><idno type="wicri:Area/Ncbi/Checkpoint">001D94</idno><idno type="wicri:doubleKey">1570-159X:2016:Zhang L:freezing:of:gait</idno><idno type="wicri:Area/Main/Merge">000352</idno><idno type="wicri:Area/Main/Curation">000351</idno><idno type="wicri:Area/Main/Exploration">000351</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Freezing of Gait in Parkinsonism and its Potential Drug Treatment</title><author><name sortKey="Zhang, Li Li" sort="Zhang, Li Li" uniqKey="Zhang L" first="Li-Li" last="Zhang">Li-Li Zhang</name><affiliation><nlm:aff id="aff1">Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao-Tong University, China. 200080</nlm:aff><wicri:noCountry code="subfield">China. 200080</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, China. 210029</nlm:aff><wicri:noCountry code="subfield">China. 210029</wicri:noCountry></affiliation></author><author><name sortKey="Canning, S Duff" sort="Canning, S Duff" uniqKey="Canning S" first="S. Duff" last="Canning">S. Duff Canning</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Psychology University of Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychology University of Toronto</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Xiao Ping" sort="Wang, Xiao Ping" uniqKey="Wang X" first="Xiao-Ping" last="Wang">Xiao-Ping Wang</name><affiliation><nlm:aff id="aff1">Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao-Tong University, China. 200080</nlm:aff><wicri:noCountry code="subfield">China. 200080</wicri:noCountry></affiliation></author></analytic><series><title level="j">Current Neuropharmacology</title><idno type="ISSN">1570-159X</idno><idno type="eISSN">1875-6190</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Samii, A" uniqKey="Samii A">A. Samii</name></author><author><name sortKey="Nutt, J G" uniqKey="Nutt J">J.G. Nutt</name></author><author><name sortKey="Ransom, B R" uniqKey="Ransom B">B.R. Ransom</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fahn, S" uniqKey="Fahn S">S. Fahn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giladi, N" uniqKey="Giladi N">N. Giladi</name></author><author><name sortKey="Nieuwboer, A" uniqKey="Nieuwboer A">A. 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Goldstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Forsaa, E B" uniqKey="Forsaa E">E.B. Forsaa</name></author><author><name sortKey="Larsen, J P" uniqKey="Larsen J">J.P. Larsen</name></author><author><name sortKey="Wentzel Larsen, T" uniqKey="Wentzel Larsen T">T. Wentzel-Larsen</name></author><author><name sortKey="Alves, G" uniqKey="Alves G">G. Alves</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teramoto, H" uniqKey="Teramoto H">H. Teramoto</name></author><author><name sortKey="Morita, A" uniqKey="Morita A">A. Morita</name></author><author><name sortKey="Ninomiya, S" uniqKey="Ninomiya S">S. Ninomiya</name></author><author><name sortKey="Shiota, H" uniqKey="Shiota H">H. Shiota</name></author><author><name sortKey="Kamei, S" uniqKey="Kamei S">S. Kamei</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li></country></list><tree><noCountry><name sortKey="Wang, Xiao Ping" sort="Wang, Xiao Ping" uniqKey="Wang X" first="Xiao-Ping" last="Wang">Xiao-Ping Wang</name><name sortKey="Zhang, Li Li" sort="Zhang, Li Li" uniqKey="Zhang L" first="Li-Li" last="Zhang">Li-Li Zhang</name></noCountry><country name="Canada"><noRegion><name sortKey="Canning, S Duff" sort="Canning, S Duff" uniqKey="Canning S" first="S. Duff" last="Canning">S. Duff Canning</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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